2015;22(2):290-6. doi:10.1016/j.phymed.2014.12.010. Milk thistle - Mayo Clinic Milk thistle is sold as an oral capsule, tablet and liquid extract. However, its currently unclear if it has the same beneficial effects in humans. The survey revealed anecdotal evidence of the improved quality of life among those who took milk thistle, despite having no measurable improvements in hepatitis symptoms like liver inflammation. Summary Milk thistle extract may help protect the liver against damage caused by disease or poisoning, though more research is needed. Epub 2013 Oct 14. Milk thistle is promoted as a dietary supplement for . However, this is the only clinical study available. Cathy Wong is a nutritionist and wellness expert. National Library of Medicine It could interact with many drugs, including some that treat high cholesterol, infections, insomnia, and blood pressure. Substances in milk thistle may reduce blood sugar, a concern for people living with diabetes. Pain in . Do not take milk thistle without medical advice if you are using a medication to treat any of the following conditions: any type of infection (including HIV, malaria, or tuberculosis); arthritis pain, occasional pain, or tension headaches (including Advil, Motrin, or Celebrex); heartburn or gastroesophageal reflux disease (GERD); high blood pressure, high cholesterol, or a heart condition; psoriasis, rheumatoid arthritis, or other autoimmune disorders; This list is not complete. It is possible to take too much, and liver toxicity has been observed in people with cancer taking silybin at very high doses (10 to 20 grams per day). Milk thistle often is used as a galactalogue, a food or supplement that people who are chest feeding take to improve milk production. If you are a Mayo Clinic patient, this could Silymarin: not just another antioxidant - PubMed It will also cover milk thistle side effects, precautions, dosage, and interactions. Satisfaction. J Tradit Complement Med. MILK THISTLE - Uses, Side Effects, and More - WebMD Additionally, the antioxidant and anti-inflammatory properties of milk thistle may also be useful for reducing the risk of developing diabetic complications like kidney disease (43). Milk thistle may have been combined with other plants or extracts in a specific preparation to treat these conditions. Matutino Santos P, Pereira Campos G, Nascimento C. Neuropsychiatr Dis Treat. Mayo Clinic does not endorse companies or products. Similar supplements to milk thistle include: Please talk with your healthcare provider about the best supplement for you. One study questioned the benefits of milk thistle for liver diseases. Advanced Milk Thistle, 120 softgels - Life Extension MILK THISTLE Reviews and User Ratings: Effectiveness, Ease of - WebMD A double-blind controlled study. Milk Thistle: Health Benefits, Side Effects, Uses, Dose - RxList Bookshelf All rights reserved. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Using different formulations together increases the risk of an overdose. Ask your doctor for advice. Song X, Zhou B, Zhang P, Lei D, Wang Y, Yao G, Hayashi T, Xia M, Tashiro S, Onodera S, Ikejima T. Neurochem Res. However, many of the studies are small and have methodological flaws, which makes it difficult to give firm guidance on this supplement or confirm its effects (46). Fluoxetine (Prozac), for instance, clocks in at roughly $16 for 21 capsules if youre buying with the drugs.com discount card, but the side effects are often not as easy to swallow (3). I have bad anxiety, mild depression and obsessive thoughts - Reddit Research on milk thistle use for specific conditions shows: Milk thistle might play a role in treating certain liver conditions. Interactions. There is also concern that milk thistle might affect estrogen levels. The benefits of milk thistle may be due to silymarin, an active ingredient found in the herb that is said to have antioxidant and anti-inflammatory effects. The flavonoid complex silymarin in preclinical studies has been found to increase serotonin and dopamine levels in the cortex. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, The 10 Best Herbs for Liver Health: Benefits and Precautions, How to Get Rid of Acne: 14 Home Remedies for Pimples. Epub 2016 Dec 22. Join 45,000+ subscribers and receive the latest, useful and exclusive health and wellness articles, health tips, special offers and more - delivered direct to your inbox. Since milk thistle may lower blood sugar, people with diabetes should check with their doctor before taking the herb as it may make their blood sugar fall too low. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Silibinin, a flavonoid derived from milk thistle (Silybum marianum), has been used as a hepato-protectant in the clinical treatment of liver diseases. Finally, those with hormone-sensitive conditions, including certain cancers, may need to avoid using milk thistle. This article reviews what milk thistle is and, Milk thistle tea is said to protect the liver, stimulate breast milk production, and lower blood sugar levels. Clinical practice shows that milk thistle has a good anti-liver injury effect and can be used to prevent anti-tuberculosis drug-induced liver injury. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. About curcumin, it isn't usually a problem but if you're on IMAOs you may like to read a bit before taking high doses. Brain Fog (anxiety, depression, ADHD), lots of medications. Do not use this product without medical advice if you are breast-feeding a baby. One important detoxifying ingredient is milk thistle. Our website services, content, and products are for informational purposes only. Before J Basic Clin Physiol Pharmacol. Bethesda, MD 20894, Web Policies Milk thistle is currently used for the treatment of toxin-induced liver injury, for its inhibition of progressive hepatic fibrosis and the prevention of cirrhosis, for its antifibrogenic effects in alcohol-induced cirrhosis and for modulation of insulin resistance. Taken in appropriate doses, oral use of milk thistle appears to be safe. Studies on cancer cell lines (done in the laboratory) have found that elements in milk thistle: Researchers also are looking at how milk thistle might complement traditional care and treatment in people diagnosed with gastrointestinal cancers. 5th ed. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Era of Hope Meeting for the Department of Defense Breast Cancer Research Program, Atlanta, June 8-11, 2000. A service of the National Library of Medicine, PubMed contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. The Gale Encyclopedia of Alternative Medicine, second edition, 2004. Historically, people have used milk thistle for liver disorders and gallbladder problems. While the cost of most OCD medications currently available on the market is actually quite reasonable, the common side effects that occur are definitely not. Neurological Disorders Milk thistle has long been used to alleviate the inflammation commonly associated with a host of neurological disorders such as dementia, Alzheimers, and Parkinsons Disease (8). In trying to determine the proper milk thistle OCD dosage, herbalists and experts tend to recommend 200-400mg divided across two or three doses per day (5). Talk to your doctor before taking any supplements because they might interfere with your medication. Milk thistle may not be recommended in some situations. However, there is no solid evidence that supports these claims. 1982;17:51721. If you have diabetes, use milk thistle with caution, since the supplement might lower blood sugar. Milk Thistle: Benefits, Uses, Side Effects, and More Silymarin, a milk thistle element, is reported safe at doses of 700 milligrams three times a day for 24 weeks. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Milk thistle is native to Europe and was introduced into North America by early colonists. 12 Health Benefits Of Milk Thistle, Nutrition, & Side Effects - STYLECRAZE Follow your healthcare provider's instructions about any restrictions on food, beverages, or activity. See additional information. Milk thistle (Silybum marianum) is a plant traditionally used as a liver tonic. Milk thistle has been shown in experimental test-tube and animal studies to stimulate bone mineralization and potentially be protective against bone loss (22, 23). Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). Silymarin is an antioxidant compound taken from milk thistle seeds. World J Gastroenterol. Milk Thistle Tea: Benefits, Side Effects, and Dosage - Healthline Summary Initial test-tube and animal studies have shown that milk thistle has some promising characteristics that could make it useful for protecting brain function. Just amazing and timely information at your fingertips. N-Acetylcysteine The data is very limited, but one randomized controlled study found that mothers taking 420 mg of silymarin for 63 days produced 64% more milk than those taking a placebo (37). Summary In animals, milk thistle has been shown to stimulate bone mineralization. People with diabetes often have high cholesterol. Certain people should take precautions when using milk thistle, and others may need to avoid it altogether. 2014;10(1):31-35. doi:10.17925/EE.2014.10.01.31. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Generic name: milk thistle [MILK-THIH-sull]

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